CCNI (gene)

AliasesCCNI, CCNI1, CYC1, CYI, cyclin I

External IDsMGI: 1341077; HomoloGene: 4979; GeneCards: CCNI; OMA:CCNI - orthologs

Chr.Chromosome 5 (mouse)^[1]

End93,354,354 bp^[1]

CCNI
Identifiers
Aliases	CCNI, CCNI1, CYC1, CYI, cyclin I
External IDs	MGI: 1341077; HomoloGene: 4979; GeneCards: CCNI; OMA:CCNI - orthologs
Gene location (Mouse) Chr. Chromosome 5 (mouse)[1] Band 5|5 E2 Start 93,329,792 bp[1] End 93,354,354 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in ganglionic eminence tail of embryo dentate gyrus of hippocampal formation granule cell ventricular zone spermatocyte cerebellar cortex primary visual cortex superior frontal gyrus ovary hippocampus proper BioGPS More reference expression data
Gene ontology Molecular function protein kinase activity cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding Cellular component cyclin-dependent protein kinase holoenzyme complex nucleus cytoplasm Biological process spermatogenesis regulation of cell cycle regulation of cyclin-dependent protein serine/threonine kinase activity mitotic cell cycle protein phosphorylation regulation of mitotic nuclear division positive regulation of cell population proliferation positive regulation of cell cycle mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10983 12453 Ensembl ENSG00000118816 ENSMUSG00000063015 UniProt Q14094 Q9Z2V9 RefSeq (mRNA) NM_006835 NM_017367 RefSeq (protein) NP_006826 NP_001335061 NP_001335062 NP_001335063 NP_001335064 NP_001335065 NP_001335066 NP_001335067 NP_001335068 NP_001335069 NP_059063 Location (UCSC) n/a Chr 5: 93.33 – 93.35 Mb PubMed search [2] [3]
Wikidata
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Cyclin-I is a protein that in humans is encoded by the CCNI gene.^[4][5]

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined.^[5]