CCT3

Protein-coding gene in humans From Wikipedia, the free encyclopedia

T-complex protein 1 subunit gamma is a protein that in humans is encoded by the CCT3 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesCCT3, CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5, chaperonin containing TCP1 subunit 3
Quick facts Available structures, PDB ...
CCT3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCCT3, CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5, chaperonin containing TCP1 subunit 3
External IDsOMIM: 600114; MGI: 104708; HomoloGene: 4373; GeneCards: CCT3; OMA:CCT3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001008800
NM_001008883
NM_005998

NM_009836

RefSeq (protein)

NP_001008800
NP_005989

NP_033966

Location (UCSC)Chr 1: 156.31 – 156.37 MbChr 3: 88.2 – 88.23 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a molecular chaperone that is member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[6]

Interactions

CCT3 has been shown to interact with PPP4C.[7][8]

References

Further reading

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