CCT8

CCT8
Identifiers
Aliases	CCT8, C21orf112, Cctq, D21S246, PRED71, chaperonin containing TCP1 subunit 8
External IDs	OMIM: 617786; MGI: 107183; HomoloGene: 4802; GeneCards: CCT8; OMA:CCT8 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	29,073,797 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	87,292,761 bp
RNA expression pattern
	Top expressed in
	oocyte; ; gonad; ; secondary oocyte; ; epithelium of nasopharynx; ; embryo; ; ganglionic eminence; ; endothelial cell; ; germinal epithelium; ; Epithelium of choroid plexus; ; ventricular zone;
	Top expressed in
	otic placode; ; otic vesicle; ; epiblast; ; mandibular prominence; ; maxillary prominence; ; saccule; ; somite; ; primitive streak; ; abdominal wall; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; ATP binding; protein folding chaperone activity; unfolded protein binding; cadherin binding;
Cellular component	cell body; cytosol; centrosome; cell projection; cilium; nucleoplasm; microtubule organizing center; zona pellucida receptor complex; intermediate filament cytoskeleton; microtubule; extracellular exosome; cytoskeleton; cytoplasm; chaperonin-containing T-complex; extracellular region; secretory granule lumen; azurophil granule lumen; ficolin-1-rich granule lumen;
Biological process	positive regulation of protein localization to Cajal body; positive regulation of establishment of protein localization to telomere; pore complex assembly; protein stabilization; positive regulation of telomere maintenance via telomerase; toxin transport; positive regulation of telomerase RNA localization to Cajal body; binding of sperm to zona pellucida; protein folding; 'de novo' protein folding; neutrophil degranulation; chaperone-mediated protein folding;
	Sources:Amigo / QuickGO
Orthologs
	10694
	12469
	ENSG00000156261
	ENSMUSG00000025613
	P50990
	P42932
	NM_006585; NM_001282907; NM_001282908; NM_001282909
	NM_009840
	NP_001269836; NP_001269837; NP_001269838; NP_006576
	NP_033970
	Wikidata
View/Edit Human	View/Edit Mouse

T-complex protein 1 subunit theta is a protein that in humans is encoded by the CCT8 gene.^[5]^[6] The CCT8 protein is a component of the TRiC complex.