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CDC42 binding protein kinase beta

Protein-coding gene in humans From Wikipedia, the free encyclopedia

CDC42 binding protein kinase beta is a protein that in humans is encoded by the CDC42BPB gene.[5]

AliasesCDC42BPB, MRCKB, CDC42 binding protein kinase beta, CHOCNS
PDBOrtholog search: PDBe RCSB
Quick facts CDC42BPB, Identifiers ...
CDC42BPB
Identifiers
AliasesCDC42BPB, MRCKB, CDC42 binding protein kinase beta, CHOCNS
External IDsOMIM: 614062; MGI: 2136459; GeneCards: CDC42BPB
Available structures
PDBOrtholog search: PDBe RCSB
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
2.7.11.1↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006035

NM_183016

RefSeq (protein)

NP_006026
NP_006026.3

NP_898837

Location (UCSC)Chr 14: 102.93 – 103.06 MbChr 12: 111.26 – 111.34 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rats suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.

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