CEP55

Centrosomal protein of 55 kDa (Cep55) is a protein that in humans is encoded by the CEP55 gene.^[5][6]

AliasesCEP55, C10orf3, CT111, URCC6, centrosomal protein 55, MARCH

External IDsOMIM: 610000; MGI: 1921357; GeneCards: CEP55

PDBOrtholog search: PDBe RCSB

Chr.Chromosome 10 (human)^[1]

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CEP55
Identifiers
Aliases	CEP55, C10orf3, CT111, URCC6, centrosomal protein 55, MARCH
External IDs	OMIM: 610000; MGI: 1921357; GeneCards: CEP55
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3E1R, 3WUT, 3WUU, 3WUV
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q23.33 Start 93,496,612 bp[1] End 93,529,092 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C2 Start 38,043,459 bp[2] End 38,062,871 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle ventricular zone gonad secondary oocyte sperm ganglionic eminence stromal cell of endometrium rectum gingival epithelium mucosa of transverse colon Top expressed in primary oocyte zygote secondary oocyte endothelial cell of lymphatic vessel spermatocyte cumulus cell atrioventricular valve medial ganglionic eminence abdominal wall ventricular zone More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm centriole centrosome cleavage furrow cytoskeleton membrane intercellular bridge midbody microtubule organizing center plasma membrane Flemming body Biological process cell division cell cycle septum digestion after cytokinesis mitotic cytokinesis mitotic metaphase plate congression nucleus organization establishment of protein localization renal system development cranial skeletal system development multicellular organism development regulation of phosphatidylinositol 3-kinase signaling midbody abscission Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 55165 74107 Ensembl ENSG00000138180 ENSMUSG00000024989 UniProt Q53EZ4 Q8BT07 RefSeq (mRNA) NM_001127182 NM_018131 NM_001164362 NM_028293 NM_028760 NM_001360663 RefSeq (protein) NP_001120654 NP_060601 NP_001157834 NP_082569 NP_083036 NP_001347592 Location (UCSC) Chr 10: 93.5 – 93.53 Mb Chr 19: 38.04 – 38.06 Mb PubMed search [3] [4]
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Cep55 is a mitotic phosphoprotein that plays a key role in cytokinesis, the final stage of cell division.^[7] and cilia formation in neural stem cells.^[8]