CFMB (drug)

CFMB (drug)
Identifiers
	IUPAC name (2S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenyl-1,3-thiazol-2-yl)butanamide;
CAS Number	1208552-99-1;
PubChem CID	46226294;
ChemSpider	24656891;
ChEMBL	ChEMBL607315;
Chemical and physical data
Formula	C21H21ClN2OS
Molar mass	384.92 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)(C)[C@@H](C1=CC=C(C=C1)Cl)C(=O)NC2=NC=C(S2)C3=CC=CC=C3;
	InChI InChI=1S/C21H21ClN2OS/c1-21(2,3)18(15-9-11-16(22)12-10-15)19(25)24-20-23-13-17(26-20)14-7-5-4-6-8-14/h4-13,18H,1-3H3,(H,23,24,25)/t18-/m0/s1; Key:ZVAPEFXSRDIMFP-SFHVURJKSA-N;

CFMB is an experimental drug which acts as a reasonably potent and selective agonist for the free fatty acid receptor FFAR2 (GPR43) with only weak activity at the closely related FFAR3 receptor. It has antiinflammatory effects and has been used to study the role of FFAR2 in regulation of gastrointestinal hormone release and immune system function.^[1]^[2]^[3]^[4]

[1]

[2]

[3]

[4]

Identifiers

IUPAC name (2S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenyl-1,3-thiazol-2-yl)butanamide
CAS Number	1208552-99-1
PubChem CID	46226294
ChemSpider	24656891
ChEMBL	ChEMBL607315
Chemical and physical data
Formula	C₂₁H₂₁ClN₂OS
Molar mass	384.92 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)(C)[C@@H](C1=CC=C(C=C1)Cl)C(=O)NC2=NC=C(S2)C3=CC=CC=C3
InChI InChI=1S/C21H21ClN2OS/c1-21(2,3)18(15-9-11-16(22)12-10-15)19(25)24-20-23-13-17(26-20)14-7-5-4-6-8-14/h4-13,18H,1-3H3,(H,23,24,25)/t18-/m0/s1 Key:ZVAPEFXSRDIMFP-SFHVURJKSA-N

Related Articles