CGB5

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Chorionic gonadotropin, beta polypeptide 5 is a protein that in humans is encoded by the CGB5 gene. [3]

PDBHuman UniProt search: PDBe RCSB
AliasesCGB5, HCG, CGB, hCGB, chorionic gonadotropin beta subunit 5, chorionic gonadotropin subunit beta 5
Quick facts Available structures, PDB ...
CGB5
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesCGB5, HCG, CGB, hCGB, chorionic gonadotropin beta subunit 5, chorionic gonadotropin subunit beta 5
External IDsOMIM: 608825; HomoloGene: 37338; GeneCards: CGB5; OMA:CGB5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_033043

n/a

RefSeq (protein)

n/a

Location (UCSC)Chr 19: 49.04 – 49.05 Mbn/a
PubMed search[2]n/a
Wikidata
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Function

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and a unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008].

References

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