CGP-37849

CGP-37849
Clinical data
Other names	CGP-37849, CGP-40116
Identifiers
	IUPAC name (E,2R)-2-amino-4-methyl-5-phosphonopent-3-enoic acid;
CAS Number	137424-81-8 ;
PubChem CID	6604869;
ChemSpider	5037128 ;
UNII	76IND1BS43;
ChEMBL	ChEMBL29811 ;
CompTox Dashboard (EPA)	DTXSID901214124 ;
Chemical and physical data
Formula	C6H12NO5P
Molar mass	209.138 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C/C(=C\[C@H](C(=O)O)N)/CP(=O)(O)O;
	InChI InChI=1S/C6H12NO5P/c1-4(3-13(10,11)12)2-5(7)6(8)9/h2,5H,3,7H2,1H3,(H,8,9)(H2,10,11,12)/b4-2+/t5-/m1/s1 ; Key:BDYHNCZIGYIOGJ-XWCPEMDWSA-N ;
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CGP-37849 is a competitive antagonist at the NMDA receptor.^[1] It is a potent, orally active anticonvulsant in animal models,^[2] and was researched for the treatment of epilepsy.^[3] It also has neuroprotective activity^[4] and shows antidepressant^[5]^[6] and anxiolytic effects.^[7]^[8]