CHRNA2

CHRNA2
Identifiers
Aliases	CHRNA2, cholinergic receptor nicotinic alpha 2 subunit
External IDs	OMIM: 118502; MGI: 87886; HomoloGene: 20193; GeneCards: CHRNA2; OMA:CHRNA2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	27,479,883 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	66,390,397 bp
RNA expression pattern
	Top expressed in
	gonad; ; lateral nuclear group of thalamus; ; secondary oocyte; ; prostate; ; prefrontal cortex; ; inferior ganglion of vagus nerve; ; right frontal lobe; ; periodontal fiber; ; renal medulla; ; bone;
	Top expressed in
	neural layer of retina; ; granulocyte; ; muscle of thigh; ; proximal tubule; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; thoracic diaphragm; ; cerebellar cortex; ; primary visual cortex; ; lobe of prostate;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	acetylcholine binding; acetylcholine receptor activity; ion channel activity; extracellular ligand-gated ion channel activity; ligand-gated ion channel activity; acetylcholine-gated cation-selective channel activity; transmembrane signaling receptor activity;
Cellular component	integral component of membrane; acetylcholine-gated channel complex; postsynaptic membrane; membrane; plasma membrane; synapse; cell junction; cell periphery; integral component of plasma membrane; neuron projection;
Biological process	protein heterooligomerization; response to nicotine; synaptic transmission, cholinergic; ion transport; neuromuscular synaptic transmission; signal transduction; regulation of postsynaptic membrane potential; excitatory postsynaptic potential; ion transmembrane transport; chemical synaptic transmission; regulation of membrane potential; nervous system process; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	1135
	110902
	ENSG00000120903
	ENSMUSG00000022041
	Q15822
	Q91X60
NM_000742; NM_001282455; NM_001347705; NM_001347706; NM_001347707;
	NM_001347708
	NM_144803
NP_000733; NP_001269384; NP_001334634; NP_001334635; NP_001334636;
	NP_001334637
	NP_659052
	Wikidata
View/Edit Human	View/Edit Mouse

Neuronal acetylcholine receptor subunit alpha-2, also known as nAChRα2, is a protein that in humans is encoded by the CHRNA2 gene.^[5]^[6] The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR).