CISD2

Protein-coding gene in humans From Wikipedia, the free encyclopedia

CDGSH iron sulfur domain 2 is a protein that in humans is encoded by the CISD2 gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesCISD2, ERIS, Miner1, NAF-1, WFS2, ZCD2, CDGSH iron sulfur domain 2
Quick facts Available structures, PDB ...
CISD2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCISD2, ERIS, Miner1, NAF-1, WFS2, ZCD2, CDGSH iron sulfur domain 2
External IDsOMIM: 611507; MGI: 1914256; HomoloGene: 36436; GeneCards: CISD2; OMA:CISD2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001008388

NM_025902

RefSeq (protein)

NP_001008389

NP_080178

Location (UCSC)Chr 4: 102.87 – 102.89 MbChr 3: 135.11 – 135.13 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011].

See also

References

Further reading

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