CL-218,872

CL-218,872 is a sedative and hypnotic drug used in scientific research.^[1][2] It has similar effects to sedative-hypnotic benzodiazepine drugs such as triazolam, but is structurally distinct and so is classed as a nonbenzodiazepine hypnotic.

CAS Number

• 66548-69-4 ^N

PubChem CID

• 107950

ChemSpider

• 97072 ^Y

UNII

• O7GR5XL5B5

Quick facts Identifiers, CAS Number ...

CL-218,872

Identifiers
IUPAC name 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[3,4-f]pyridazine
CAS Number	66548-69-4 N
PubChem CID	107950
ChemSpider	97072 Y
UNII	O7GR5XL5B5
ChEMBL	ChEMBL13662 Y
CompTox Dashboard (EPA)	DTXSID80216728
ECHA InfoCard	100.164.099
Chemical and physical data
Formula	C13H9F3N4
Molar mass	278.238 g·mol−1
InChI InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3 Y Key:GUOQUXNJZHGPQF-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

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CL-218,872 is a GABA_A partial agonist which is selective for the α1 subtype.^[3][4][5] It has a range of effects including sedative, hypnotic, anxiolytic, anticonvulsant and amnestic actions, however the most prominent actions are sedation and amnesia, and CL-218,872 produces effects very similar to those of the hypnotic imidazopyridine derivative zolpidem in animal studies.^[6][7][8]