CLDN15

CLDN15
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4P79
Identifiers
Aliases	CLDN15, claudin 15
External IDs	OMIM: 615778; MGI: 1913103; HomoloGene: 8646; GeneCards: CLDN15; OMA:CLDN15 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	101,238,820 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	137,004,712 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; mucosa of ileum; ; germinal epithelium; ; mucosa of transverse colon; ; granulocyte; ; parietal pleura; ; right lobe of liver; ; left uterine tube; ; spleen;
	Top expressed in
	duodenum; ; crypt of lieberkuhn of small intestine; ; intestinal villus; ; granulocyte; ; jejunum; ; Paneth cell; ; epithelium of small intestine; ; ileum; ; left colon; ; oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural molecule activity; identical protein binding;
Cellular component	integral component of membrane; cell junction; plasma membrane; lateral plasma membrane; membrane; bicellular tight junction;
Biological process	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; ion transport;
	Sources:Amigo / QuickGO
Orthologs
	24146
	60363
	ENSG00000106404
	ENSMUSG00000001739
	P56746
	Q9Z0S5
	NM_138429; NM_001185080; NM_014343
	NM_021719
	NP_001172009; NP_055158
	NP_068365
	Wikidata
View/Edit Human	View/Edit Mouse

Claudin-15 is a protein that in humans is encoded by the CLDN15 gene.^[5] It belongs to the group of claudins. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways and Tight junction. GO annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is CLDN10.^[6]