CNOT11

CNOT11
Identifiers
Aliases	CNOT11, C2orf29, C40, CCR4-NOT transcription complex subunit 11
External IDs	MGI: 106580; HomoloGene: 9711; GeneCards: CNOT11; OMA:CNOT11 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	101,270,316 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	39,585,970 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; mucosa of ileum; ; myocardium of left ventricle; ; tibialis anterior muscle; ; rectum; ; body of pancreas; ; mucosa of transverse colon; ; cardiac muscle tissue of right atrium; ; granulocyte;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; hand; ; epiblast; ; spermatocyte; ; zygote; ; interventricular septum; ; superior cervical ganglion; ; endocardial cushion; ; Gonadal ridge;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	cytoplasm; cytosol; nucleus; CCR4-NOT complex;
Biological process	nuclear-transcribed mRNA poly(A) tail shortening; gene silencing; cell population proliferation; regulation of transcription, DNA-templated; regulation of translation; transcription, DNA-templated; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;
	Sources:Amigo / QuickGO
Orthologs
	55571
	52846
	ENSG00000158435
	ENSMUSG00000003135
	Q9UKZ1
	Q9CWN7
	NM_017546
	NM_028043
	NP_060016
	NP_082319
	Wikidata
View/Edit Human	View/Edit Mouse

CCR4-NOT transcription complex subunit 11 is a protein that in humans is encoded by the CNOT11 gene.^[5] It is a subunit of the CCR4-Not deadenylase complex.