CRADD

CRADD
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2O71, 2OF5, 3CRD
Identifiers
Aliases	CRADD, MRT34, RAIDD, CASP2 and RIPK1 domain containing adaptor with death domain
External IDs	OMIM: 603454; MGI: 1336168; HomoloGene: 2821; GeneCards: CRADD; OMA:CRADD - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	93,894,840 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	95,159,995 bp
RNA expression pattern
	Top expressed in
	testicle; ; left ventricle; ; right lobe of liver; ; apex of heart; ; gonad; ; islet of Langerhans; ; right auricle of heart; ; right testis; ; left testis; ; left adrenal gland;
	Top expressed in
	granulocyte; ; genital tubercle; ; muscle of thigh; ; right kidney; ; proximal tubule; ; tail of embryo; ; Ileal epithelium; ; cardiac muscle tissue of left ventricle; ; medial ganglionic eminence; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein-macromolecule adaptor activity; protein binding; protease binding; death domain binding;
Cellular component	cytoplasm; nucleus; cytosol;
Biological process	cellular response to mechanical stimulus; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; positive regulation of apoptotic signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; extrinsic apoptotic signaling pathway via death domain receptors; signal transduction; apoptotic process; regulation of apoptotic process; positive regulation of apoptotic process; apoptotic signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	8738
	12905
	ENSG00000169372
	ENSMUSG00000045867
	P78560; Q8IY43
	O88843
	NM_003805; NM_001320099; NM_001320100; NM_001320101; NM_001330126
	NM_009950; NM_001330138; NM_001330141; NM_001330175
NP_001307028; NP_001307029; NP_001307030; NP_001317055; NP_003796;
	NP_001307028.1
	NP_001317067; NP_001317070; NP_001317104; NP_034080
	Wikidata
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