CRLF3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Cytokine receptor-like factor 3 is a protein that in humans is encoded by the CRLF3 gene.[5]

AliasesCRLF3, CREME-9, CREME9, CRLM9, CYTOR4, FRWS, p48.2, cytokine receptor like factor 3
End30,824,692 bp[1]
Quick facts Identifiers, Aliases ...
CRLF3
Identifiers
AliasesCRLF3, CREME-9, CREME9, CRLM9, CYTOR4, FRWS, p48.2, cytokine receptor like factor 3
External IDsOMIM: 614853; MGI: 1860086; HomoloGene: 9327; GeneCards: CRLF3; OMA:CRLF3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015986

NM_001277106
NM_018776

RefSeq (protein)

NP_057070

NP_001264035
NP_061246

Location (UCSC)Chr 17: 30.77 – 30.82 MbChr 11: 79.94 – 79.97 Mb
PubMed search[3][4]
Wikidata
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Function

Although CRLF3 signaling pathways have not yet been fully characterized it is very likely that CRLF3 is a neuroprotective erythropoietin receptor.[6]

Origin

Phylogenetic analyses have shown that CRLF3 at first appeared in a common ancestor of Cnidaria and Bilateria and hence emerged with the origin of the nervous system.[7][8]

References

Further reading

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