CTNNBL1

Beta-catenin-like protein 1 is a protein that in humans is encoded by the CTNNBL1 gene.^[5][6]

PDBOrtholog search: PDBe RCSB

AliasesCTNNBL1, C20orf33, NAP, P14L, PP8304, dJ633O20.1, catenin beta like 1, IMD99

External IDsOMIM: 611537; MGI: 1913892; HomoloGene: 12003; GeneCards: CTNNBL1; OMA:CTNNBL1 - orthologs

Chr.Chromosome 20 (human)^[1]

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CTNNBL1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4CB8, 4CB9, 4CBA, 4HM9, 4HNM, 4MFU, 4MFV
Identifiers
Aliases	CTNNBL1, C20orf33, NAP, P14L, PP8304, dJ633O20.1, catenin beta like 1, IMD99
External IDs	OMIM: 611537; MGI: 1913892; HomoloGene: 12003; GeneCards: CTNNBL1; OMA:CTNNBL1 - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q11.23 Start 37,693,955 bp[1] End 37,872,129 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 H1|2 78.4 cM Start 157,579,321 bp[2] End 157,733,534 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis spleen monocyte ganglionic eminence apex of heart granulocyte ventricular zone right auricle of heart muscle layer of sigmoid colon Top expressed in otic vesicle spermatid primary oocyte saccule spermatocyte otic placode primitive streak seminiferous tubule renal corpuscle medullary collecting duct More reference expression data BioGPS More reference expression data
Gene ontology Molecular function enzyme binding protein binding Cellular component cytoplasm spliceosomal complex membrane nucleus Prp19 complex nucleoplasm Biological process positive regulation of apoptotic process mRNA splicing, via spliceosome mRNA processing somatic diversification of immunoglobulins apoptotic process RNA splicing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56259 66642 Ensembl ENSG00000132792 ENSMUSG00000027649 UniProt Q8WYA6 Q9CWL8 RefSeq (mRNA) NM_001281495 NM_030877 NM_025680 RefSeq (protein) NP_001268424 NP_110517 NP_079956 Location (UCSC) Chr 20: 37.69 – 37.87 Mb Chr 2: 157.58 – 157.73 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs. In addition, the encoded protein contains Armadillo/beta-catenin-like repeats, which have been implicated in protein-protein interactions. Although the function of this protein has not been determined, the C-terminal portion of the protein has been shown to possess apoptosis-inducing activity.^[6] It is a housekeeping gene.