CYP105 family
Group of cytochrome P450 enzymes
From Wikipedia, the free encyclopedia
Cytochrome P450, family 105, also known as CYP105, is a cytochrome P450 monooxygenase family in bacteria, predominantly found in the phylum Actinomycetota and the order Actinomycetales.[2][3] The first three genes and subfamilies identified in this family is the herbicide-inducible P-450SU1 (CYP105A1, subfamily A) and P-450SU2 (CYP105B1, subfamily B) from Streptomyces griseolus[4][5] and choP (CYP105C1, subfamily C) from Streptomyces sp's cholesterol oxidase promoter region.[6][1]
Subfamily
| Subfamily[7] | first gene identified | Species | REF |
|---|---|---|---|
| A | SU1 (CYP105A1) | Streptomyces griseolus | [4] |
| B | SU2 (CYP105B1) | Streptomyces griseolus | [4] |
| C | choP (CYP105C1) | Streptomyces sp | [6] |
| D | soyC (CYP105D1) | Streptomyces griseus | [8] |
| E | ORF1 (CYP105E1) | Rhodococcus fascians | [9] |
Application
CYP105 enzymes is widely used in industry, such as the production of pravastatin.[3]
