Calbindin 1

Protein found in humans From Wikipedia, the free encyclopedia

Calbindin 1 is a protein that in humans is encoded by the CALB1 gene. It belongs to the calbindin family of calcium-binding proteins, along with calretinin (CALB2).[5]

Quick facts CALB1, Identifiers ...
CALB1
Identifiers
AliasesCALB1, CALB, D-28K, calbindin 1
External IDsOMIM: 114050; MGI: 88248; HomoloGene: 21026; GeneCards: CALB1; OMA:CALB1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004929
NM_001366795

NM_009788

RefSeq (protein)

NP_004920
NP_001353724

NP_033918

Location (UCSC)Chr 8: 90.06 – 90.1 MbChr 4: 15.88 – 15.91 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability.[6] This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015].

References

Further reading

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