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Canocapavir

Pharmaceutical compound From Wikipedia, the free encyclopedia

Canocapavir is an investigational new drug that is being evaluated by Zhimeng Biopharma for the treatment of Hepatitis B infections.[1] It is an HBV capsid assembly inhibitor.[2][3][4]

Other namesZM-H1505R
Legal status
  • investigational
Quick facts Clinical data, Other names ...
Canocapavir
Clinical data
Other namesZM-H1505R
Legal status
Legal status
  • investigational
Identifiers
  • (2R)-2-[1-(4-bromophenyl)-3-(4-fluorophenyl)pyrazol-4-yl]-3-[2-(2-oxo-1,3-dihydrobenzimidazol-5-yl)ethyl]-1,3-oxazolidin-4-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
Chemical and physical data
FormulaC27H21BrFN5O3
Molar mass562.399 g·mol−1
3D model (JSmol)
  • C1C(=O)N([C@H](O1)C2=CN(N=C2C3=CC=C(C=C3)F)C4=CC=C(C=C4)Br)CCC5=CC6=C(C=C5)NC(=O)N6
  • InChI=InChI=1S/C27H21BrFN5O3/c28-18-4-8-20(9-5-18)34-14-21(25(32-34)17-2-6-19(29)7-3-17)26-33(24(35)15-37-26)12-11-16-1-10-22-23(13-16)31-27(36)30-22/h1-10,13-14,26H,11-12,15H2,(H2,30,31,36)/t26-/m1/s1
  • Key:YGPZZDKSASSELG-AREMUKBSSA-N
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Clinical trials

Phase 3 clinical trials of canocapavir for the treatment of chronic HBV infections are planned.[5]

See also

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