Capillin
Chemical compound
From Wikipedia, the free encyclopedia
Capillin is a toxic naturally occurring organic compound with the chemical formula C
12H
8O. The structure contains acetophenone and a polyyne (pentadiynyl) portion, conjugated together as an ynone.
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| Names | |
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| Preferred IUPAC name
1-Phenylhexa-2,4-diyn-1-one | |
| Other names
Capillin | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C12H8O | |
| Molar mass | 168.195 g·mol−1 |
| Melting point | 82–83 °C (180–181 °F; 355–356 K) |
| 0.0177 mg/mL | |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
1 mg/kg (IV, mice)[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical taxonomy
Capillin is found in the essential oil of a number of Artemisia species, including Artemisia monosperma and Artemisia dracunculus (tarragon).[2] The substance was initially isolated from Artemisia capillaris in 1956.[3]
Applications
Capillin is a biologically active substance. It has strong antifungal activity, and it is possibly antitumoral. Capillin exhibits cytotoxic activity and could cause apoptosis of certain human tumor cells.[4]