Caras y Caretas published its first edition on 3 August 2001.[1] In February 2017, a reporter for the magazine had her head grazed by a bullet shot by two individuals on a motorcycle, according to the Committee to Protect Journalists.[2]
In 2020, the magazine launched a streaming service that had about 20,000 subscribers, with its main program being titled "Legitimate defense".[3]
By its twentieth anniversary in 2021, it had published 1,027 consecutive editions every Friday.[1] A twentieth anniversary edition of the magazine was placed in the Legislative Library of Uruguay.[4] In 2021, Caras y Caretas criticized President Luis Lacalle Pou, saying that the president sought to see the magazine "dead."[1]
In 2023, prosecutor Gabriela Fossati filed a defamation complaint against Alberto Grille, director of Caras y Caretas, after he described her as a "cowardice" with her verdict against Alejandro Astesiano, the security chief of President Luis Lacalle Pou.[5]
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