Carnitine palmitoyltransferase II

Mammalian protein found in humans From Wikipedia, the free encyclopedia

Carnitine O-palmitoyltransferase 2, mitochondrial is an enzyme that in humans is encoded by the CPT2 gene.[5][6]

AliasesCPT2, CPT1, CPTASE, IIAE4, carnitine palmitoyltransferase 2
External IDsOMIM: 600650; MGI: 109176; GeneCards: CPT2
End53,214,197 bp[1]
Quick facts CPT2, Identifiers ...
CPT2
Identifiers
AliasesCPT2, CPT1, CPTASE, IIAE4, carnitine palmitoyltransferase 2
External IDsOMIM: 600650; MGI: 109176; GeneCards: CPT2
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
2.3.1.21
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000098
NM_001330589

NM_009949

RefSeq (protein)

NP_000089
NP_001317518

NP_034079

Location (UCSC)Chr 1: 53.2 – 53.21 MbChr 4: 107.76 – 107.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

Carnitine palmitoyltransferase II precursor (CPT2) is a mitochondrial membrane protein which is transported to the mitochondrial inner membrane. CPT2 together with carnitine palmitoyltransferase I oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders and carnitine palmitoyltransferase II deficiency.[6]

Acyl-CoA from cytosol to the mitochondrial matrix

See also

References

Further reading

Related Articles

Wikiwand AI