She was the founding Vice President of the National Association of Scholars, and an editor of Academic Questions, the quarterly publication of NAS. She was a regular contributor at the Phi Beta Cons blog at National Review Online.
In 1991 President George H. W. Bush nominated her to be on the board of the National Endowment for the Humanities, which was strongly opposed by officers of the Modern Language Association and other academics; they argued that she was not a distinguished scholar.[3][4] She had virtually no record of publication in scholarly journals, and had never authored a scholarly book. The campaign against her, backed by many liberal academics and by Sen. Edward Kennedy, succeeded in defeating her nomination.
Iannone's interests have gone beyond literature. In her article, "Bryan was right", she wrote that Christians are mistaken when they say that God and Darwinian evolution are compatible.
In recent years she wrote increasingly on issues of national identity, criticizing the neoconservative belief that America is an idea rather as a culture. She served on the board of directors of the Center for Immigration Studies.
