Ceftizoxime

Chemical compound From Wikipedia, the free encyclopedia

Ceftizoxime is a third-generation cephalosporin available for parenteral administration.[1] Unlike other third-generation cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. It rather resembles cefotaxime in its properties, but is not subject to metabolism. It was removed from the US Market in 2007.

ATC code
Quick facts Clinical data, Trade names ...
Ceftizoxime
Clinical data
Trade namesCefizox
AHFS/Drugs.comConsumer Drug Information
MedlinePlusa684043
ATC code
Identifiers
  • (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.210.846 Edit this at Wikidata
Chemical and physical data
FormulaC13H13N5O5S2
Molar mass383.40 g·mol−1
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Synthesis

Injectable third generation cephalosporin antibiotic related to cefotaxime, q.v. Exhibits broad spectrum activity and resistance to β-lactamase hydrolysis.

Ceftizoxime synthesis:[2][3]

References

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