Centromere protein O
Protein-coding gene in the species Homo sapiens
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An Error has occurred retrieving Wikidata item for infobox Centromere protein O is a protein that in humans is encoded by the CENPO gene.[1][2][3] CENPO is involved in cell proliferation and cell cycle progression and has been shown to be down-regulated in trisomic neurospheres a mouse model of Down Syndrome, resulting in reduced numbers of neural progenitors and neuroblasts and a severe reduction in numbers of neurons produced.[4]