Ceramide synthase 4
From Wikipedia, the free encyclopedia
| Ceramide synthase 4 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CerS4 | ||||||
| Alt. symbols | LASS4 | ||||||
| NCBI gene | 79603 | ||||||
| HGNC | 23747 | ||||||
| OMIM | 615334 | ||||||
| RefSeq | NM_024552.2 | ||||||
| UniProt | Q9HA82 | ||||||
| Other data | |||||||
| EC number | 2.3.1.24 | ||||||
| Locus | Chr. 19 p13.3 | ||||||
| |||||||
Ceramide synthase 4 (CerS4) is an enzyme that in humans is encoded by the CERS4 gene and is one of the least studied of the ceramide synthases.
CerS4 synthesizes ceramides containing C18-22 fatty acids in a fumonisin B1-independent manner.[1] It is expressed at highest levels in skin, leukocytes, heart and liver, although at much lower levels than other ceramide synthases.[2]