Chlorocitric acid
Chemical compound
From Wikipedia, the free encyclopedia
Chlorocitric acid is a organochlorine compound, a derivative of citric acid, belonging to the group of tricarboxylic acids and their derivatives, characterized by the presence of three carboxyl groups.[1] Its chemical formula is C6H7ClO7.[2][3]
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| Names | |
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| IUPAC name
1-chloro-2-hydroxypropane-1,2,3-tricarboxylic acid | |
| Other names
Chlorocitrate, (−)-threo-chlorocitric acid | |
| Identifiers | |
3D model (JSmol) |
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| UNII | |
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| Properties | |
| C6H7ClO7 | |
| Molar mass | 226.57 g·mol−1 |
| soluble | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Natural occurrence
The acid has been detected in human blood. Chlorocitric acid is not a naturally occurring metabolite; it is found exclusively in individuals who have been exposed to this compound or its derivatives. From a scientific perspective, chlorocitric acid is considered to be part of the human exposome, which encompasses all exposures that individuals encounter throughout their lifetime and their impact on health. These exposures begin before birth and include environmental and occupational factors.[4]
Synthesis
Chlorocitric acid is obtained by the action of hypochlorous acid on aconitic acid in aqueus solution.[5]
Physical properties
The acid is uncrystallizible, soluble in water and ether. The compound decomposes when heated, releasing hydrochloric acid and oxycitric acid.[5]
Uses
There are reports suggesting that chlorocitric acid might be used as an anti-obesity agent.[6][7]