Chloroethylene oxide
From Wikipedia, the free encyclopedia
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| Other names
2-chlorooxirane, CEO | |
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CompTox Dashboard (EPA) |
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| Properties | |
| C2H3ClO | |
| Molar mass | 78.50 g·mol−1 |
| Appearance | colorless liquid |
| Boiling point | 40–55 °C (104–131 °F; 313–328 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chloroethylene oxide is the organic compound with the formula ClC2H3O. It is the epoxide of vinyl chloride. The compound is rarely observed, but it is widely proposed as a metabolite of vinyl chloride, formed by the action of cytochrome-P450. It is significant because it causes DNA alkylation. It isomerizes to chloroacetaldehyde, which modifies adenosine residues by conversion to 1,N6-ethenodeoxyadenosine (εdA).[1][2]
