Chlorohydroxyphenylglycine

Chlorohydroxyphenylglycine
Names
	IUPAC name Amino(2-chloro-5-hydroxyphenyl)acetic acid
Identifiers
CAS Number	170846-74-9 ; 1303993-73-8 (sodium salt) ;
3D model (JSmol)	Interactive image;
Abbreviations	CHPG
ChemSpider	2879711;
ECHA InfoCard	100.162.133
IUPHAR/BPS	1417;
PubChem CID	3645780;
UNII	LSA5YS5PNZ ;
CompTox Dashboard (EPA)	DTXSID60394614 ;
	InChI InChI=1S/C8H8ClNO3/c9-6-2-1-4(11)3-5(6)7(10)8(12)13/h1-3,7,11H,10H2,(H,12,13) Key: UNIDAFCQFPGYJJ-UHFFFAOYSA-N; InChI=1/C8H8ClNO3/c9-6-2-1-4(11)3-5(6)7(10)8(12)13/h1-3,7,11H,10H2,(H,12,13) Key: UNIDAFCQFPGYJJ-UHFFFAOYAM;
	SMILES Clc1ccc(O)cc1C(N)C(=O)O;
Properties
Chemical formula	C8H6ClNO3
Molar mass	199.59 gÂ·molâ1
	Except where otherwise noted, data are given for materials in their standard state (at 25 Â°C [77 Â°F], 100 kPa). Infobox references

2-Chloro-5-hydroxyphenylglycine or CHPG is an agonist of the metabotropic glutamate receptors, specific for mGluR5.^[1]

Quick facts Names, Identifiers ...

Close

It is capable of directly potentiating the depolarization of hippocampal CA1 neurons induced through NMDA administration.^[2]

References