The endogenous development of the parasite occurs in the cells of the bile epithelium.
The infected host cell becomes hypertrophic and emerges above the epithelial surface. This hypertrophy coincides with a drastic depletion of the microvilli. The junction zone along with the underlying cell extends into numerous long and fine membranal out-folds.
Meront: These undergo binary fission.
Microgamont: The differentiating microgamont develops an expanded multilobed body.
Macrogamont: The organelles include type 1 and type 2 wall forming bodies, canaliculi and granular bodies.
Oocyte: The oocyst wall forms from 4 wall-membranes consolidating over the zygote plasmalemma. The oocysts possess four sporocysts each containing two sporozoites.
These species possess bivalved sporocysts and lack a Stieda body.