Chondrocalcinosis
From Wikipedia, the free encyclopedia
Chondrocalcinosis or cartilage calcification is calcification (accumulation of calcium salts) in hyaline cartilage and/or fibrocartilage.[1] Chondrocalcinosis is an observation that can be visualized through diagnostic imaging tests such as X-rays, CT, MRI, and ultrasound.[2]
Buildup of calcium phosphate in the ankle joints has been found in about 50% of the general population, and may be associated with osteoarthritis.[3]
Another common cause of chondrocalcinosis is calcium pyrophosphate dihydrate crystal deposition disease (CPPD).[4] CPPD is estimated to affect 4–7% of the adult populations of Europe and the United States.[5] Chondrocalcinosis can be seen in approximately 40% of those with CPPD.[6] Previous studies have overestimated the prevalence by simply estimating the prevalence of chondrocalcinosis regardless of cause.[5]
A magnesium deficiency may cause chondrocalcinosis, and there is anecdotal evidence that magnesium supplementation may reduce or alleviate symptoms.[7] In some cases, arthritis from injury can cause chondrocalcinosis.[8] Other causes of chondrocalcinosis include:[4]
Symptoms
Chondrocalcinosis does not always lead to symptoms. However, chondrocalcinosis in the presence of CPPD may cause symptoms similar to Pseudogout, Pseudo-rheumatoid arthritis, and Pseudo-osteoarthritis. Chondrocalcinosis may be accompanied by joint pain, joint swelling, and decreased range of motion.[9]
Chondrocalcinosis sites
Chondrocalcinosis affects common areas such as the knee, wrist, hand, and pelvis.[10] Chondrocalcinosis can also be visualized affecting the spine. "Crowned Dens Syndrome" is an example of chondrocalcinosis affecting cervical vertebrae.[11]
