Chromosome engineering
From Wikipedia, the free encyclopedia
Chromosome engineering is "the controlled generation of chromosomal deletions, inversions, or translocations with defined endpoints."[1] By combining chromosomal translocation, chromosomal inversion, and chromosomal deletion, chromosome engineering has been shown to identify the underlying genes that cause certain diseases in mice. In coming years, it is very likely that chromosomal engineering will be able to do the same identification for diseases in humans, as well as all other organisms.[2]
| chromosomal deletion | chromosomal inversion | chromosomal translocation |
|---|---|---|
| Chromosomal deletion is a mutation (a genetic aberration) in which a part of a chromosome or a sequence of DNA is missing.[citation needed] | Chromosomal inversion is a chromosome rearrangement in which a segment of a chromosome is reversed end to end.[citation needed] | Chromosomal translocation is a chromosome abnormality caused by rearrangement of parts between nonhomologous chromosomes.[citation needed] |