Cinchona calisaya
Species of plant
From Wikipedia, the free encyclopedia
Cinchona calisaya is a species of shrub or tree in the family Rubiaceae.[2] It is native to the forests of the eastern slopes of the Andes, where they grow from 200–3,300 metres (660–10,830 ft) in elevation in Peru and Bolivia.[2] The species is known for a high quinine content, a key antimalarial alkaloid. From the 1860s, it was grown in plantations (under the synonym C. ledgeriana Wedd.) in the Dutch East Indies to supply the global quinine trade.[3]
| Cinchona calisaya | |
|---|---|
 | |
| Branchlets with flowers and fruits | |
Scientific classification  | |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Clade: | Asterids |
| Order: | Gentianales |
| Family: | Rubiaceae |
| Genus: | Cinchona |
| Species: | C. calisaya |
| Binomial name | |
| Cinchona calisaya Wedd. | |
 | |
| Distribution range | |
| Synonyms | |
|
C. ledgeriana[1] | |
Toxicity
Cinchona bark and its quinine alkaloids can cause cardiac sodium and potassium channel blockade, CNS and renal toxicity. Cinchonism trio: GI upset, headaches, and tinnitus. Ventricular arrhythmias, hypoglycemia, renal failure, respiratory failure, jaundice and death.[4]
