Hume's first group show was held in 1944 at the Saskatoon Art Centre. Her paintings are largely landscapes and still lifes, and can be found represented in the collections of the Saskatchewan Arts Board, Mendel Art Gallery (now, Remai Modern), Winnipeg Art Gallery, Saskatoon Public School Board, the National Gallery of Canada Canadian Museum of Contemporary Photography, and in private collections.[5] From 1964 to 1975, She organized elementary school programs for children in Saskatoon through a partnership with the Mendel Art Gallery. She exhibited her works with the Saskatoon Art Association and the Regina Women's Artists Association in the 1940s. She was a member of the Saskatoon Camera Club and the namesake of the Transparency Battle trophy.[6]
A collection of her paintings of Great Plains flora, which were acquired by the Mendel Art Gallery in 1975, were exhibited as part of An apology, a pill, a ritual, a resistance (2021) in the Remai Modern Gallery.[7] The plants featured in the collection have medicinal uses, some widely known, and others which are sacred knowledge of First Nations and Métis Medicine people.[8][9]