Cloforex

Cloforex (Oberex) is an anorectic of the amphetamine class.^[1] It is a prodrug to chlorphentermine.^[2] It never became a mass produced drug in part due to the side effects found in mice. Mice who consumed 75 mg of cloforex a day experienced weight loss along with pulmonary hypertension and hair loss.^[3]

Trade namesFrenapyl, Lipociden, Oberex, Vidipon, Zeisin

Other namesCarbamic acid, N-[2-(4-chlorophenyl)-1,1-dimethylethyl]-, ethyl ester

Routes of
administrationOral

ATC code

• none

Quick facts Clinical data, Trade names ...

Cloforex

Clinical data
Trade names	Frenapyl, Lipociden, Oberex, Vidipon, Zeisin
Other names	Carbamic acid, N-[2-(4-chlorophenyl)-1,1-dimethylethyl]-, ethyl ester
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name ethyl N-[1-(4-chlorophenyl)-2-methylpropan-2-yl]carbamate
CAS Number	14261-75-7
PubChem CID	26602
ChemSpider	24781
UNII	2QJT5ZC1L6
ChEMBL	ChEMBL1697686
CompTox Dashboard (EPA)	DTXSID7048794
ECHA InfoCard	100.034.659
Chemical and physical data
Formula	C13H18ClNO2
Molar mass	255.74 g·mol−1
3D model (JSmol)	Interactive image
Melting point	89 °C (192 °F)
Boiling point	52.75 °C (126.95 °F)
SMILES CCOC(=O)NC(C)(C)CC1=CC=C(C=C1)Cl

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