Collagen, type XIX, alpha 1

Collagen alpha-1(XIX) chain is a protein that in humans is encoded by the COL19A1 gene.^[5][6][7]

AliasesCOL19A1, COL9A1L, D6S228E, collagen type XIX alpha 1, collagen type XIX alpha 1 chain

External IDsOMIM: 120165; MGI: 1095415; GeneCards: COL19A1

Chr.Chromosome 6 (human)^[1]

End70,212,468 bp^[1]

Quick facts COL19A1, Identifiers ...

COL19A1
Identifiers
Aliases	COL19A1, COL9A1L, D6S228E, collagen type XIX alpha 1, collagen type XIX alpha 1 chain
External IDs	OMIM: 120165; MGI: 1095415; GeneCards: COL19A1
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q13 Start 69,866,556 bp[1] End 70,212,468 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 A5 Start 24,300,971 bp[2] End 24,626,553 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad gastric mucosa endothelial cell epithelium of nasopharynx cerebellar vermis right hemisphere of cerebellum cartilage tissue tibialis anterior muscle lymph node Top expressed in facial skeleton primary motor cortex rib tunica media of zone of aorta Dermatocranium mammillary body lateral part of occipital bone CA3 field perirhinal cortex membranous bone More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-macromolecule adaptor activity extracellular matrix structural constituent extracellular matrix structural constituent conferring tensile strength Cellular component endoplasmic reticulum lumen collagen extracellular region extracellular matrix extracellular space collagen-containing extracellular matrix Biological process collagen catabolic process multicellular organism development skeletal system development cell differentiation muscle organ development skeletal muscle tissue development extracellular matrix organization cell adhesion cell-cell adhesion Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 1310 12823 Ensembl ENSG00000082293 ENSMUSG00000026141 UniProt Q14993 Q0VF58 RefSeq (mRNA) NM_001858 NM_007733 RefSeq (protein) NP_001849 NP_031759 Location (UCSC) Chr 6: 69.87 – 70.21 Mb Chr 1: 24.3 – 24.63 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Close

This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced.^[7]