CopA-like RNA
Family of non-coding RNAs found on the R1 pyramid
From Wikipedia, the free encyclopedia
CopA-like RNA is a family of non-coding RNAs found on the R1 plasmid.
| CopA-like RNA | |
|---|---|
Predicted secondary structure and sequence conservation of CopA | |
| Identifiers | |
| Symbol | CopA |
| Rfam | RF00042 |
| Other data | |
| RNA type | Gene; antisense |
| Domain | Bacteria |
| SO | SO:0000644 |
| PDB structures | PDBe |
In several groups of bacterial plasmids, antisense RNAs regulate copy number through inhibition of replication initiator protein synthesis. These RNAs are characterised by a long hairpin structure interrupted by several unpaired nucleotides or bulged loops. In plasmid R1, the inhibitory complex between the antisense RNA (CopA) and its target mRNA (CopT) is characterised by a four-way junction structure and a side-by-side helical alignment.[1][2][3]
See also
Plasmid-mediated resistance (sRNA section)
