Cottonwood Slough-Dry Run
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| Cottonwood Slough- Dry Run | |
|---|---|
  Cottonwood Slough- Dry Run  Cottonwood Slough- Dry Run | |
| Location | Lake County, South Dakota |
| Coordinates | 44°57′26″N 97°11′37″W / 44.9571°N 97.1935°W |
| Basin countries | United States |
| Surface area | 6,424 acres (26.00 km2)[1] |
| Designated | 1975 |
Cottonwood Slough-Dry Run is a glacial wetland adjacent to Lake Kampeska in Roberts County, South Dakota, United States. The complex is located near Watertown in eastern South Dakota. Owned by the State of South Dakota and the private sector, the wetland was listed as a National Natural Landmark in 1975.