Cyanonilutamide

Cyanonilutamide (developmental code name RU-56279) is a nonsteroidal antiandrogen which was never marketed.^[1][2] Both RU-56187 and RU-58841 appear to be prodrugs of cyanonilutamide in vivo in animals.^[2] It has relatively low affinity for the androgen receptor but nonetheless shows significant antiandrogenic activity in animals.^[2]

Other namesRU-56279

Drug classNonsteroidal antiandrogen

CAS Number

• 143782-20-1 ^Y

PubChem CID

• 11162285

Quick facts Clinical data, Other names ...

Cyanonilutamide

Clinical data
Other names	RU-56279
Drug class	Nonsteroidal antiandrogen
Identifiers
IUPAC name 4-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
CAS Number	143782-20-1 Y
PubChem CID	11162285
ChemSpider	9337385
UNII	6PAG4TC385
ChEMBL	ChEMBL146858
CompTox Dashboard (EPA)	DTXSID901143349
Chemical and physical data
Formula	C13H10F3N3O2
Molar mass	297.237 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)C#N)C(F)(F)F)C
InChI InChI=1S/C13H10F3N3O2/c1-12(2)10(20)19(11(21)18-12)8-4-3-7(6-17)9(5-8)13(14,15)16/h3-5H,1-2H3,(H,18,21) Key:CYCKLVAQENOQPG-UHFFFAOYSA-N

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