Cyheptamide

Anticonvulsant compound made from dibenzosuberone From Wikipedia, the free encyclopedia

Cyheptamide was a investigational new drug that was developed by Ayerst Research Laboratories in the 1960s and was evaluated as an anticonvulsant.[1]

Other namesCyheptamine
CAS Number
Quick facts Clinical data, Other names ...
Cyheptamide
Clinical data
Other namesCyheptamine
Identifiers
  • tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.027.792 Edit this at Wikidata
Chemical and physical data
FormulaC16H15NO
Molar mass237.302 g·mol−1
3D model (JSmol)
  • C1CC2=CC=CC=C2C(C3=CC=CC=C31)C(=O)N
  • InChI=1S/C16H15NO/c17-16(18)15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H2,17,18)
  • Key:APBVLLORZMAWKI-UHFFFAOYSA-N
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Cyheptamide undergoes significant metabolic transformation in both animals and humans, primarily through hydroxylation pathways.[2]

Cyheptamide exhibits moderate acute toxicity in animal models, with species-specific variations in lethal dose values.[3]

SGB-017 has a similar chemical structure and has also been evaluated for its potential use as an anticonvulsant.[4]

Chemical structure of SGB-017

See also

References

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