D-161

Chemical compound From Wikipedia, the free encyclopedia

D-161[1] is a chemical known in research circles as a triple reuptake inhibitor. Although this compound has lent support to the inclusion of dopamine in the monoamine hypothesis of depression, D-161 has not been tested in clinical trials.

CAS Number
FormulaC25H27NO2
Quick facts Identifiers, CAS Number ...
D-161
Identifiers
  • 4-((((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC25H27NO2
Molar mass373.496 g·mol−1
3D model (JSmol)
  • Oc2ccc(cc2)CNC(CC3)COC3C(c1ccccc1)c4ccccc4
  • InChI=1S/C25H27NO2/c27-23-14-11-19(12-15-23)17-26-22-13-16-24(28-18-22)25(20-7-3-1-4-8-20)21-9-5-2-6-10-21/h1-12,14-15,22,24-27H,13,16-18H2/t22-,24-/m0/s1
  • Key:CFCFEXCFOQWYQK-UPVQGACJSA-N
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A more recent study was reported.[2]

A couple of patents are also disclosed.[3][4]

Synthesis

The synthesis of this agent has been reported.[5][6]

References

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