D-iditol 2-dehydrogenase
From Wikipedia, the free encyclopedia
In enzymology, a d-iditol 2-dehydrogenase (EC 1.1.1.15) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are D-iditol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are D-sorbose, reduced NADH, and a proton.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is d-iditol:NAD+ 2-oxidoreductase. This enzyme is also called d-sorbitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.
