D-xylose reductase

D-xylose reductase (EC 1.1.1.307, XylR, XyrA, msXR, dsXR, monospecific xylose reductase, dual specific xylose reductase, NAD(P)H-dependent xylose reductase, xylose reductase) is an enzyme with systematic name xylitol:NAD(P)⁺ oxidoreductase.^{[1][2][3][4][5][6][7][8]} This enzyme catalyses the following chemical reaction

xylitol

+ NAD⁺

 

 

 

H⁺

 

H⁺

 

D-xylose

+ NADH

 

EC no.1.1.1.307

BRENDAenzyme data

ExPASyNiceZyme view

KEGGenzyme entry

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D-xylose reductase
Identifiers
EC no.	1.1.1.307
Databases
BRENDA	enzyme data
ExPASy	NiceZyme view
KEGG	enzyme entry
MetaCyc	metabolic pathway
Rhea	reactions
PDB structures	RCSB PDB PDBe PDBsum
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Xylose reductase catalyses the initial reaction in the xylose utilization pathway. The enzyme can use nicotinamide adenine dinucleotide (NADH) or nicotinamide adenine dinucleotide phosphate (NADPH) as its cofactor.^[9]