DAM-57

DAM-57, also known as N,N-dimethyllysergamide (DAM) or as lysergic acid dimethylamide, is a derivative of ergine. There has been a single report of observing N,N-dimethyl-D-lysergamide in the illicit drug market.^[2] This compound did induce autonomic disturbances at oral levels of some 10 times the dose required for lysergic acid diethylamide (LSD), presumably in the high hundreds of micrograms. There is some disagreement as to whether there were psychic changes observed.^[1] It was first described in the scientific literature by Albert Hofmann and colleagues by 1955.^[3]

Other namesDAM-57; N,N-Dimethyllysergamide; DAM; Lysergic acid dimethylamide

Routes of
administrationOral^[1]

Legal status

• US: Schedule I Controlled in the United States via the Federal Analog Act but only if it is intended for human consumption.

CAS Number

• 4238-84-0 ^Y

Quick facts Clinical data, Other names ...

DAM-57

Clinical data
Other names	DAM-57; N,N-Dimethyllysergamide; DAM; Lysergic acid dimethylamide
Routes of administration	Oral[1]
Legal status
Legal status	US: Schedule I Controlled in the United States via the Federal Analog Act but only if it is intended for human consumption.
Identifiers
IUPAC name (6aR,9R)-N,N-dimethyl-7-methyl-4,6,6a,7,8,9- hexahydroindolo- [4,3-fg] quinoline- 9-carboxamide
CAS Number	4238-84-0 Y
PubChem CID	199478
ChemSpider	172668 Y
UNII	LX5MKR2EXX
CompTox Dashboard (EPA)	DTXSID30962445
Chemical and physical data
Formula	C18H21N3O
Molar mass	295.386 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(N(C)C)[C@@H]3C=C2c4cccc1c4c(c[nH]1)C[C@H]2N(C3)C
InChI InChI=1S/C18H21N3O/c1-20(2)18(22)12-7-14-13-5-4-6-15-17(13)11(9-19-15)8-16(14)21(3)10-12/h4-7,9,12,16,19H,8,10H2,1-3H3/t12-,16-/m1/s1 Y Key:FWHSERNVTGTIJE-MLGOLLRUSA-N Y
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