DAP (gene)

Death-associated protein 1 is a protein that in humans is encoded by the DAP gene.^[5][6][7]

AliasesDAP, death associated protein

External IDsOMIM: 600954; MGI: 1918190; HomoloGene: 3235; GeneCards: DAP; OMA:DAP - orthologs

Chr.Chromosome 5 (human)^[1]

End10,761,234 bp^[1]

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DAP
Identifiers
Aliases	DAP, death associated protein
External IDs	OMIM: 600954; MGI: 1918190; HomoloGene: 3235; GeneCards: DAP; OMA:DAP - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5p15.2 Start 10,679,230 bp[1] End 10,761,234 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 B2 Start 31,224,460 bp[2] End 31,274,487 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas stromal cell of endometrium islet of Langerhans gallbladder right coronary artery thoracic aorta ascending aorta left adrenal gland right adrenal cortex left adrenal cortex Top expressed in transitional epithelium of urinary bladder calvaria gastrula blood pyloric antrum pancreas islet of Langerhans left lobe of liver ankle body of femur More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 1611 223453 Ensembl ENSG00000112977 ENSMUSG00000039168 UniProt P51397 Q91XC8 RefSeq (mRNA) NM_004394 NM_001291963 NM_146057 RefSeq (protein) NP_001278892 NP_004385 NP_666169 Location (UCSC) Chr 5: 10.68 – 10.76 Mb Chr 15: 31.22 – 31.27 Mb PubMed search [3] [4]
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DAP gene encodes a basic, proline-rich, 15-kD protein. Death-associated protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma.^[7]