Deleted in bladder cancer protein 1 is a protein that in humans is encoded by the DBC1 gene.[5][6][7][8][9]
AliasesBRINP1, DBC1, DBCCR1, FAM5A, BMP/retinoic acid inducible neural specific 1 Quick facts BRINP1, Identifiers ...
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This gene is located within chromosome 9 (9q32-33), a chromosomal region that frequently shows loss of heterozygosity in transitional cell carcinoma of the bladder. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.[7]
The functions of this gene are unknown, and it has not yet been placed in a protein family or functional pathway. Nonetheless, it is suspected to act as a tumor suppressor gene.
