DCHS2

Protein dachsous homolog 2, also known as protocadherin-23 (PCDH23) or cadherin-27 (CDH27), is a protein that in humans is encoded by the DCHS2 gene.^[3][4]

AliasesDCHS2, CDH27, CDHJ, CDHR7, PCDH23, PCDHJ, dachsous cadherin-related 2

External IDsOMIM: 612486; HomoloGene: 130686; GeneCards: DCHS2; OMA:DCHS2 - orthologs

Chr.Chromosome 4 (human)^[1]

End154,491,799 bp^[1]

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DCHS2
Identifiers
Aliases	DCHS2, CDH27, CDHJ, CDHR7, PCDH23, PCDHJ, dachsous cadherin-related 2
External IDs	OMIM: 612486; HomoloGene: 130686; GeneCards: DCHS2; OMA:DCHS2 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q31.3 Start 154,231,742 bp[1] End 154,491,799 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex Achilles tendon superior frontal gyrus nucleus accumbens smooth muscle tissue muscle layer of sigmoid colon sural nerve body of uterus myometrium caudate nucleus n/a More reference expression data BioGPS n/a
Gene ontology Molecular function calcium ion binding molecular function cadherin binding Cellular component integral component of membrane plasma membrane membrane cellular component Biological process cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules biological process cell-cell adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54798 n/a Ensembl ENSG00000197410 ENSG00000284227 n/a UniProt Q6V1P9 n/a RefSeq (mRNA) NM_001142552 NM_001142553 NM_017639 NM_199348 NM_001358235 n/a RefSeq (protein) NP_001136024 NP_001345164 n/a Location (UCSC) Chr 4: 154.23 – 154.49 Mb n/a PubMed search [2] n/a
Wikidata
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DCHS2 has been implicated in the nose angle (how much a nose is upturned).^[5] As well as facial genetics ^[6][7]