DDX27

DDX27
Identifiers
Aliases	DDX27, DRS1, Drs1p, PP3241, RHLP, dJ686N3.1, HSPC259, DEAD-box helicase 27
External IDs	OMIM: 616621; MGI: 2385884; GeneCards: DDX27
Enzyme activity
Gene location (Human)
Chr.	Chromosome 20 (human)
End	49,244,077 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	166,876,867 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; pancreatic ductal cell; ; endothelial cell; ; sural nerve; ; hair follicle; ; mucosa of ileum; ; left ovary; ; right ovary; ; pylorus; ; sperm;
	Top expressed in
	epiblast; ; otic placode; ; primitive streak; ; yolk sac; ; tail of embryo; ; embryo; ; otic vesicle; ; morula; ; saccule; ; embryo;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; hydrolase activity; ATP binding; helicase activity; nucleic acid binding; RNA binding;
Cellular component	nucleolus; nucleus; chromosome; cytoplasm;
Biological process	rRNA processing; RNA secondary structure unwinding; ribosome biogenesis;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	55661
	228889
	ENSG00000124228
	ENSMUSG00000017999
	Q96GQ7
	Q921N6
	NM_017895; NM_001348187
	NM_153065
	NP_060365; NP_001335116
	NP_694705
	Wikidata
View/Edit Human	View/Edit Mouse

DEAD (Asp-Glu-Ala-Asp) box polypeptide 27, also known as DDX27, is a human gene.^[5]

AliasesDDX27, DRS1, Drs1p, PP3241, RHLP, dJ686N3.1, HSPC259, DEAD-box helicase 27

End49,244,077 bp^[1]

Quick facts Identifiers, Aliases ...

Close

The protein encoded by this gene belongs to the family of DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, the function of which has not been determined.^[5]

References