DGKB
Mammalian protein found in Homo sapiens
From Wikipedia, the free encyclopedia
Diacylglycerol kinase beta is an enzyme that in humans is encoded by the DGKB gene.[4][5]
External IDsOMIM: 604070; MGI: 2442474; HomoloGene: 37875; GeneCards: DGKB; OMA:DGKB - orthologs
Function
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene.[5]
