DMPU
Chemical compound
From Wikipedia, the free encyclopedia
N,Nâ²-Dimethylpropyleneurea (DMPU) is a cyclic urea sometimes used as a polar, aprotic organic solvent. Along with the dimethylethyleneurea, it was introduced as an analog of tetramethylurea.[2]
| Names | |
|---|---|
| Preferred IUPAC name
1,3-Dimethyl-1,3-diazinan-2-one[1] | |
| Other names
N,Nâ²-Dimethyl-N,Nâ²-trimethyleneurea N,Nâ²-Dimethylpropyleneurea 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone | |
| Identifiers | |
3D model (JSmol) |
|
| Abbreviations | DMPU |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.027.841 |
| EC Number |
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PubChem CID |
|
CompTox Dashboard (EPA) |
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| Properties | |
| C6H12N2O | |
| Molar mass | 128.175 g·molâ1 |
| Density | 1.064 g/cm3 |
| Melting point | â20 °C; â4 °F; 253 K |
| Boiling point | 246.5 °C (475.7 °F; 519.6 K) (Source) |
| miscible | |
Refractive index (nD) |
1.4875-1.4895 |
| Hazards | |
| GHS labelling: | |
| Danger | |
| H302, H318, H361f | |
| P201, P202, P264, P270, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P405, P501 | |
| Flash point | 121 °C (250 °F; 394 K) |
| Safety data sheet (SDS) | External MSDS |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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In 1985, Dieter Seebach showed that it is possible to replace the suspected carcinogen hexamethylphosphoramide (HMPA) with DMPU.[3]

